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Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution

Kynurenine aminotransferase II (KAT-II) is a 47 kDa pyridoxal phosphate (PLP)-dependent enzyme, active as a homodimer, which catalyses the transamination of the amino acids kynurenine (KYN) and 3-hydroxykynurenine (3-HK) in the tryptophan pathway, and is responsible for producing metabolites that le...

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Detalles Bibliográficos
Autores principales: Nematollahi, Alireza, Sun, Guanchen, Harrop, Stephen J., Hanrahan, Jane R., Church, W. Bret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848902/
https://www.ncbi.nlm.nih.gov/pubmed/27023527
http://dx.doi.org/10.3390/ijms17040446