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Aripiprazole and Haloperidol Activate GSK3β-Dependent Signalling Pathway Differentially in Various Brain Regions of Rats

Aripiprazole, a dopamine D(2) receptor (D(2)R) partial agonist, possesses a unique clinical profile. Glycogen synthase kinase 3β (GSK3β)-dependent signalling pathways have been implicated in the pathophysiology of schizophrenia and antipsychotic drug actions. The present study examined whether aripi...

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Detalles Bibliográficos
Autores principales: Pan, Bo, Huang, Xu-Feng, Deng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848915/
https://www.ncbi.nlm.nih.gov/pubmed/27043526
http://dx.doi.org/10.3390/ijms17040459