Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which play a pivotal role in invasion, migration, and angiogenesis of glioma. Therefore, controlling MMPs is potentially an important therapeutic strategy for glioma. In the present study, we found that exogenous cell-pe...

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Detalles Bibliográficos
Autores principales: Jung, Ji-Sun, Ahn, Young-Ho, Moon, Byung-In, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848933/
https://www.ncbi.nlm.nih.gov/pubmed/27043542
http://dx.doi.org/10.3390/ijms17040477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848933/
https://www.ncbi.nlm.nih.gov/pubmed/27043542
http://dx.doi.org/10.3390/ijms17040477

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