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Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which play a pivotal role in invasion, migration, and angiogenesis of glioma. Therefore, controlling MMPs is potentially an important therapeutic strategy for glioma. In the present study, we found that exogenous cell-pe...

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Detalles Bibliográficos
Autores principales:	Jung, Ji-Sun, Ahn, Young-Ho, Moon, Byung-In, Kim, Hee-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848933/ https://www.ncbi.nlm.nih.gov/pubmed/27043542 http://dx.doi.org/10.3390/ijms17040477

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