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Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines

In the course of searching for bioactive secondary metabolites from marine fungi, TMC-256C1 was isolated from an ethyl acetate extract of the marine-derived fungus Aspergillus sp. SF6354. TMC-256C1 displayed anti-neuroinflammatory effect in BV2 microglial cells induced by lipopolysaccharides (LPS) a...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Cheol, Cho, Kwang-Ho, Ko, Wonmin, Yoon, Chi-Su, Sohn, Jae Hak, Yim, Joung Han, Kim, Youn-Chul, Oh, Hyuncheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848985/
https://www.ncbi.nlm.nih.gov/pubmed/27070586
http://dx.doi.org/10.3390/ijms17040529