Structural Investigation for Optimization of Anthranilic Acid Derivatives as Partial FXR Agonists by in Silico Approaches

In this paper, a three level in silico approach was applied to investigate some important structural and physicochemical aspects of a series of anthranilic acid derivatives (AAD) newly identified as potent partial farnesoid X receptor (FXR) agonists. Initially, both two and three-dimensional quantit...

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Detalles Bibliográficos
Autores principales: Chen, Meimei, Yang, Xuemei, Lai, Xinmei, Kang, Jie, Gan, Huijuan, Gao, Yuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848992/
https://www.ncbi.nlm.nih.gov/pubmed/27070594
http://dx.doi.org/10.3390/ijms17040536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848992/
https://www.ncbi.nlm.nih.gov/pubmed/27070594
http://dx.doi.org/10.3390/ijms17040536

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