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Structural Investigation for Optimization of Anthranilic Acid Derivatives as Partial FXR Agonists by in Silico Approaches

In this paper, a three level in silico approach was applied to investigate some important structural and physicochemical aspects of a series of anthranilic acid derivatives (AAD) newly identified as potent partial farnesoid X receptor (FXR) agonists. Initially, both two and three-dimensional quantit...

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Detalles Bibliográficos
Autores principales:	Chen, Meimei, Yang, Xuemei, Lai, Xinmei, Kang, Jie, Gan, Huijuan, Gao, Yuxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848992/ https://www.ncbi.nlm.nih.gov/pubmed/27070594 http://dx.doi.org/10.3390/ijms17040536

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