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SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations

Predicting the effect of amino acid substitutions on protein–protein affinity (typically evaluated via the change of protein binding free energy) is important for both understanding the disease-causing mechanism of missense mutations and guiding protein engineering. In addition, researchers are also...

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Detalles Bibliográficos
Autores principales: Petukh, Marharyta, Dai, Luogeng, Alexov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849003/
https://www.ncbi.nlm.nih.gov/pubmed/27077847
http://dx.doi.org/10.3390/ijms17040547