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SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations
Predicting the effect of amino acid substitutions on protein–protein affinity (typically evaluated via the change of protein binding free energy) is important for both understanding the disease-causing mechanism of missense mutations and guiding protein engineering. In addition, researchers are also...
Autores principales: | Petukh, Marharyta, Dai, Luogeng, Alexov, Emil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849003/ https://www.ncbi.nlm.nih.gov/pubmed/27077847 http://dx.doi.org/10.3390/ijms17040547 |
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