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Beyond the Niche: Myelodysplastic Syndrome Topobiology in the Laboratory and in the Clinic

We review the murine and human microenvironment and hematopoietic stem cell niche in the context of intact bone marrow architecture in man and mouse, both in normal and in myelodysplastic syndrome marrow. We propose that the complexity of the hematopoietic stem cell niche can usefully be approached...

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Detalles Bibliográficos
Autores principales: Flores-Figueroa, Eugenia, Gratzinger, Dita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849009/
https://www.ncbi.nlm.nih.gov/pubmed/27089321
http://dx.doi.org/10.3390/ijms17040553