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Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death and its prognosis remains poor due to the high risk of tumor recurrence and metastasis. Berberine (BBR) is a natural compound derived from some medicinal plants, and accumulating evidence has shown its potent anti-tum...

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Detalles Bibliográficos
Autores principales: Wang, Xuanbin, Wang, Ning, Li, Hongliang, Liu, Ming, Cao, Fengjun, Yu, Xianjun, Zhang, Jingxuan, Tan, Yan, Xiang, Longchao, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849033/
https://www.ncbi.nlm.nih.gov/pubmed/27092498
http://dx.doi.org/10.3390/ijms17040577