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Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes

BACKGROUND: 1,2,4-Triazole3-thiones are good scaffolds for preparation of new lead compounds. Their derivatives attracted the attention of chemists due to their wide spectrum of biological activities. Alkylsulfanyl-1,2,4-triazoles have three nucleophilic sites (nitrogens) ready for reaction with ele...

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Detalles Bibliográficos
Autores principales: Boraei, Ahmed T. A., El Ashry, El Sayed H., Duerkop, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849090/
https://www.ncbi.nlm.nih.gov/pubmed/27127538
http://dx.doi.org/10.1186/s13065-016-0165-0