Cargando…

Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes

BACKGROUND: 1,2,4-Triazole3-thiones are good scaffolds for preparation of new lead compounds. Their derivatives attracted the attention of chemists due to their wide spectrum of biological activities. Alkylsulfanyl-1,2,4-triazoles have three nucleophilic sites (nitrogens) ready for reaction with ele...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boraei, Ahmed T. A., El Ashry, El Sayed H., Duerkop, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849090/ https://www.ncbi.nlm.nih.gov/pubmed/27127538 http://dx.doi.org/10.1186/s13065-016-0165-0

Ejemplares similares

A new synthetic access to 2-N-(glycosyl)thiosemicarbazides from 3-N-(glycosyl)oxadiazolinethiones and the regioselectivity of the glycosylation of their oxadiazolinethione precursors
por: El Ashry, El Sayed H, et al.
Publicado: (2013)

Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles
por: Gautun, Odd R., et al.
Publicado: (2001)

Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles.
por: Jørgensen, Kåre B., et al.
Publicado: (2001)

Synthesis and Screening of New [1,3,4]Oxadiazole, [1,2,4]Triazole, and [1,2,4]Triazolo[4,3-b][1,2,4]triazole Derivatives as Potential Antitumor Agents on the Colon Carcinoma Cell Line (HCT-116)
por: Abdelrehim, El-sayed M.
Publicado: (2021)

Synthesis of a New Series of Nitrogen/Sulfur Heterocycles by Linking Four Rings: Indole; 1,2,4-Triazole; Pyridazine; and Quinoxaline
por: Boraei, Ahmed T. A., et al.
Publicado: (2020)

Regioselective Synthesis of 1-(2,6-Dichloro-4-Trifluoromethyl-phenyl)-4-Alkyl-1H-[1,2,3]-Triazoles
por: Hu, Huanan, et al.
Publicado: (2008)

Synthesis of New Bioactive Indolyl-1,2,4-Triazole Hybrids As Dual Inhibitors for EGFR/PARP-1 Targeting Breast and Liver Cancer Cells
por: Youssef, Mohamed F., et al.
Publicado: (2022)

Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
por: Guengerich, F P, et al.
Publicado: (1987)

Crystal structures of five 1-alkyl-4-aryl-1,2,4-triazol-1-ium halide salts
por: Guino-o, Marites A., et al.
Publicado: (2015)

Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols
por: Al-Abdullah, Ebtehal S, et al.
Publicado: (2014)

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles
por: Colanceska-Ragenovic, Katica, et al.
Publicado: (2001)

The Reactivity of Phosphanylphosphinidene Complexes of Transition Metals Toward Terminal Dihaloalkanes
por: Ordyszewska, Anna, et al.
Publicado: (2020)

Synthesis of 4-Alkyl-4H-1,2,4-triazole Derivatives by Suzuki Cross-Coupling Reactions and Their Luminescence Properties
por: Olesiejuk, Monika, et al.
Publicado: (2019)

Novel Hybrid 1,2,4- and 1,2,3-Triazoles Targeting Mycobacterium Tuberculosis Enoyl Acyl Carrier Protein Reductase (InhA): Design, Synthesis, and Molecular Docking
por: El Sawy, Maged A., et al.
Publicado: (2022)

Regioselective Synthesis of 5-Trifluoromethyl 1,2,4-Triazoles via [3 + 2]-Cycloaddition of Nitrile Imines with CF(3)CN
por: Lin, Bo, et al.
Publicado: (2022)

5-Amino-3-(4H-1,2,4-triazol-4-yl)-1H-1,2,4-triazole
por: Liu, Bing, et al.
Publicado: (2012)

Synthesis of New Functionalized Indoles Based on Ethyl Indol-2-carboxylate
por: Boraei, Ahmed T. A., et al.
Publicado: (2016)

Syntheses and crystal structures of two adamantyl-substituted 1,2,4-triazole-5-thione N-Mannich bases
por: Al-Alshaikh, Monirah A., et al.
Publicado: (2017)

Regioselective microwave synthesis and derivatization of 1,5-diaryl-3-amino-1,2,4-triazoles and a study of their cholinesterase inhibition properties
por: Santos, Sabrina Neves, et al.
Publicado: (2019)

Two decades of the synthesis of mono- and bis-aminomercapto[1,2,4]triazoles
por: Riyadh, Sayed M., et al.
Publicado: (2020)

Regioselective Synthesis of New Family of 2-Substituted 1,2,3-Triazoles and Study of Their Fluorescent Properties
por: Muzalevskiy, Vasiliy M., et al.
Publicado: (2023)

Synthesis, Characterization and Antifungal Evaluation of 5-Substituted-4-Amino-1,2,4-Triazole-3-Thioesters
por: Hasan, Aurangzeb, et al.
Publicado: (2011)

Synthesis and Biological Activity of Substituted Urea and Thiourea Derivatives Containing 1,2,4-Triazole Moieties
por: Kocyigit-Kaymakcioglu, Bedia, et al.
Publicado: (2013)

Synthesis, Cytotoxic, and Computational Screening of Some Novel Indole–1,2,4-Triazole-Based S-Alkylated N-Aryl Acetamides
por: Zahoor, Ameer Fawad, et al.
Publicado: (2023)

4-(1,2,4-Triazol-1-yl)aniline
por: Fun, Hoong-Kun, et al.
Publicado: (2010)

Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds
por: Boraei, Ahmed T. A., et al.
Publicado: (2019)

[Hydrogen bis(1,2,4-triazole)] 1,2,4-triazolium bis(3-carboxy-4-hydroxybenzenesulfonate) 1,2,4-triazole disolvate
por: Qiu, Ming-qiang
Publicado: (2010)

An insight on medicinal attributes of 1,2,4-triazoles
por: Aggarwal, Ranjana, et al.
Publicado: (2020)

1,2,4-Triazoles as Important Antibacterial Agents
por: Strzelecka, Małgorzata, et al.
Publicado: (2021)

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of 1,2,4-Triazole-Based 4-Thiazolidinones
por: Ahmed, Sahar, et al.
Publicado: (2016)

Regioselective Pd-catalyzed α-alkylation of furans using alkyl iodides
por: Yuan, Jiaqi, et al.
Publicado: (2021)

Synthesis and Pharmacological Activities of Some New 3-Substituted-4-Amino-5-Mercapto-1,2,4-Triazoles
por: Desai, Shobha R., et al.
Publicado: (2011)

Poly[(μ(3)-hydrogenphosphato)(4H-1,2,4-triazole-κN (1))zinc]
por: Aitenneite, Hafid, et al.
Publicado: (2012)

Regioselective Fluorination of 7-Oxo-1,2,4-benzotriazines Using Selectfluor
por: Mirallai, Styliana I., et al.
Publicado: (2019)

1H-1,2,4-Triazole-3-carboxamide
por: Xie, Qing-Ruo
Publicado: (2008)

3-Nitro-1H-1,2,4-triazole
por: Hemamalini, Madhukar, et al.
Publicado: (2010)

Effect of Linker Elongation on the VGSC Affinity and Anticonvulsant Activity among 4-Alkyl-5-aryl-1,2,4-triazole-3-thione Derivatives
por: Paruch, Kinga, et al.
Publicado: (2023)

3-(Adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)-thione
por: El-Emam, Ali A., et al.
Publicado: (2012)

1-{4-[(1H-1,2,4-Triazol-1-yl)methyl]benzyl}-1H-1,2,4-triazol-4-ium perchlorate
por: Hu, Zhao-Jian, et al.
Publicado: (2010)

Synthesis and Antibacterial Evaluation of New Thione Substituted 1,2,4-Triazole Schiff Bases as Novel Antimicrobial Agents
por: Akbari Dilmaghani, Karim, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hqv34s7j8gdje2p1efq9nqav1f