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Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein
Members of the bcl-2 protein family share regions of sequence similarity, the bcl-2 homology (BH) domains. Bcl-2, the most studied member of this family, has four BH domains, BH1–4, and has a critical role in resistance to antineoplastic drugs by regulating the mitochondrial apoptotic pathway. Moreo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849145/ https://www.ncbi.nlm.nih.gov/pubmed/26866271 http://dx.doi.org/10.1038/cddis.2015.357 |