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The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells

Immunogenic cell death (ICD) evoked by chemotherapeutic agents implies emission of selected damage-associated molecular patterns (DAMP) such as cell surface exposure of calreticulin, secretion of ATP and HMGB1. We sought to verify whether miR-27a is implicated in ICD, having demonstrated that it dir...

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Detalles Bibliográficos
Autores principales: Colangelo, T, Polcaro, G, Ziccardi, P, Muccillo, L, Galgani, M, Pucci, B, Rita Milone, M, Budillon, A, Santopaolo, M, Mazzoccoli, G, Matarese, G, Sabatino, L, Colantuoni, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849155/
https://www.ncbi.nlm.nih.gov/pubmed/26913599
http://dx.doi.org/10.1038/cddis.2016.29