p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells

The Wnt inhibitor Dickkopf-1 (DKK-1) has been associated with the occurrence of bone metastases in osteotropic prostate cancer by inhibiting osteoblastogenesis. P38 mitogen-activated protein kinase (MAPK) activity is also dysregulated in advanced prostate cancer. However, the impact of p38 MAPK sign...

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Detalles Bibliográficos
Autores principales: Browne, A J, Göbel, A, Thiele, S, Hofbauer, L C, Rauner, M, Rachner, T D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849158/
https://www.ncbi.nlm.nih.gov/pubmed/26913608
http://dx.doi.org/10.1038/cddis.2016.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849158/
https://www.ncbi.nlm.nih.gov/pubmed/26913608
http://dx.doi.org/10.1038/cddis.2016.32

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