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Attenuation of the programmed cell death-1 pathway increases the M1 polarization of macrophages induced by zymosan

Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that delivers negative signals on interaction with its 2 ligands, PD-L1 and PD-L2. We assessed the contribution of the PD-1 pathway to regulating the polarization of macrophages that promote inflammation induced by zymosan. We found...

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Detalles Bibliográficos
Autores principales: Chen, W, Wang, J, Jia, L, Liu, J, Tian, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849159/
https://www.ncbi.nlm.nih.gov/pubmed/26913605
http://dx.doi.org/10.1038/cddis.2016.33