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Chimeric antigen receptor T-cell therapy for solid tumors

Chimeric antigen receptor (CAR) T cells are engineered constructs composed of synthetic receptors that direct T cells to surface antigens for subsequent elimination. Many CAR constructs are also manufactured with elements that augment T-cell persistence and activity. To date, CAR T cells have demons...

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Detalles Bibliográficos
Autores principales: Newick, Kheng, Moon, Edmund, Albelda, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849432/
https://www.ncbi.nlm.nih.gov/pubmed/27162934
http://dx.doi.org/10.1038/mto.2016.6