Cargando…

Postsynaptic density levels of the NMDA receptor NR1 subunit and PSD-95 protein in prefrontal cortex from people with schizophrenia

BACKGROUND: There is converging evidence of involvement of N-methyl-d-aspartate (NMDA) receptor hypofunction in the pathophysiology of schizophrenia. Our group recently identified a decrease in total NR1 mRNA and protein expression in the dorsolateral prefrontal cortex in a case-control study of ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Catts, Vibeke Sørensen, Derminio, Dominique Suzanne, Hahn, Chang-Gyu, Weickert, Cynthia Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849460/
https://www.ncbi.nlm.nih.gov/pubmed/27336043
http://dx.doi.org/10.1038/npjschz.2015.37