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Postsynaptic density levels of the NMDA receptor NR1 subunit and PSD-95 protein in prefrontal cortex from people with schizophrenia
BACKGROUND: There is converging evidence of involvement of N-methyl-d-aspartate (NMDA) receptor hypofunction in the pathophysiology of schizophrenia. Our group recently identified a decrease in total NR1 mRNA and protein expression in the dorsolateral prefrontal cortex in a case-control study of ind...
Autores principales: | Catts, Vibeke Sørensen, Derminio, Dominique Suzanne, Hahn, Chang-Gyu, Weickert, Cynthia Shannon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849460/ https://www.ncbi.nlm.nih.gov/pubmed/27336043 http://dx.doi.org/10.1038/npjschz.2015.37 |
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