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The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects

BACKGROUND: Metabolic syndrome may be related to folate’s pharmacogenetically regulated metabolism and atypical antipsychotic (AAP) exposure. AIMS: We examined folate supplementation on metabolic measures, endothelial functioning (Reactive Hyperemia Index (RHI)), and global methylation in AAP-treate...

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Detalles Bibliográficos
Autores principales: Ellingrod, Vicki L, Grove, Tyler B, Burghardt, Kyle J, Taylor, Stephan F, Dalack, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849464/
https://www.ncbi.nlm.nih.gov/pubmed/27336047
http://dx.doi.org/10.1038/npjschz.2015.46