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The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin

To maintain genome stability, cells pack large portions of their genome into silent chromatin or heterochromatin. Histone H3 lysine 9 methylation, a hallmark of heterochromatin, is recognized by conserved readers called chromodomains. But how chromodomains interact with their actual binding partner,...

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Detalles Bibliográficos
Autores principales: Zocco, Manuel, Marasovic, Mirela, Pisacane, Paola, Bilokapic, Silvija, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849473/
https://www.ncbi.nlm.nih.gov/pubmed/27462451
http://dx.doi.org/10.1038/celldisc.2016.4