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The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin
To maintain genome stability, cells pack large portions of their genome into silent chromatin or heterochromatin. Histone H3 lysine 9 methylation, a hallmark of heterochromatin, is recognized by conserved readers called chromodomains. But how chromodomains interact with their actual binding partner,...
Autores principales: | Zocco, Manuel, Marasovic, Mirela, Pisacane, Paola, Bilokapic, Silvija, Halic, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849473/ https://www.ncbi.nlm.nih.gov/pubmed/27462451 http://dx.doi.org/10.1038/celldisc.2016.4 |
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