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Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis
A major goal of human genetics is to elucidate the genetic architecture of human disease, with the goal of fueling improvements in diagnosis and the understanding of disease pathogenesis. The degree to which epistasis, or non-additive effects of risk alleles at different loci, accounts for common di...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849581/ https://www.ncbi.nlm.nih.gov/pubmed/27123867 http://dx.doi.org/10.1371/journal.pgen.1006003 |