Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA(2) in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia

Lysophosphatidic acid (LPA) acts on LPA(2) receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA(2) attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA(2) alone can lead to malignant transformati...

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Detalles Bibliográficos
Autores principales: Yoshida, Michihiro, He, Peijian, Yun, C. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849659/
https://www.ncbi.nlm.nih.gov/pubmed/27124742
http://dx.doi.org/10.1371/journal.pone.0154527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849659/
https://www.ncbi.nlm.nih.gov/pubmed/27124742
http://dx.doi.org/10.1371/journal.pone.0154527

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