Cargando…

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

Hepatitis C virus (HCV) particles closely mimic human very-low-density lipoproteins (VLDL) to evade humoral immunity and to facilitate cell entry. However, the principles that govern HCV association with VLDL components are poorly defined. Using an siRNA screen, we identified ABHD5 (α/β hydrolase do...

Descripción completa

Detalles Bibliográficos
Autores principales: Vieyres, Gabrielle, Welsch, Kathrin, Gerold, Gisa, Gentzsch, Juliane, Kahl, Sina, Vondran, Florian W. R., Kaderali, Lars, Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849665/
https://www.ncbi.nlm.nih.gov/pubmed/27124600
http://dx.doi.org/10.1371/journal.ppat.1005568