Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Developments in genome‐wide association studies and the increasing availability of summary genetic association data have made application of Mendelian randomization relatively straightforward. However, obtaining reliable results from a Mendelian randomization investigation remains problematic, as th...

Descripción completa

Detalles Bibliográficos
Autores principales: Bowden, Jack, Davey Smith, George, Haycock, Philip C., Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849733/
https://www.ncbi.nlm.nih.gov/pubmed/27061298
http://dx.doi.org/10.1002/gepi.21965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849733/
https://www.ncbi.nlm.nih.gov/pubmed/27061298
http://dx.doi.org/10.1002/gepi.21965

Ejemplares similares