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Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
Developments in genome‐wide association studies and the increasing availability of summary genetic association data have made application of Mendelian randomization relatively straightforward. However, obtaining reliable results from a Mendelian randomization investigation remains problematic, as th...
Autores principales: | Bowden, Jack, Davey Smith, George, Haycock, Philip C., Burgess, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849733/ https://www.ncbi.nlm.nih.gov/pubmed/27061298 http://dx.doi.org/10.1002/gepi.21965 |
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