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Evidence of Inbreeding in Hodgkin Lymphoma

Genome-wide association studies (GWASs) have identified several, mainly co-dominantly acting, single-nucleotide polymorphisms (SNPs) associated with Hodgkin lymphoma (HL). We searched for recessively acting disease loci by performing an analysis of runs of homozygosity (ROH) based on windows of homo...

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Detalles Bibliográficos
Autores principales: Thomsen, Hauke, Inacio da Silva Filho, Miguel, Fuchs, Michael, Ponader, Sabine, Pogge von Strandmann, Elke, Eisele, Lewin, Herms, Stefan, Hoffmann, Per, Engert, Andreas, Hemminki, Kari, Försti, Asta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849743/
https://www.ncbi.nlm.nih.gov/pubmed/27123581
http://dx.doi.org/10.1371/journal.pone.0154259