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Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo

Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) encodes miRNAs from intragenomic Pol III promoters. The BLV miRNAs are abundant...

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Detalles Bibliográficos
Autores principales: Gillet, Nicolas A., Hamaidia, Malik, de Brogniez, Alix, Gutiérrez, Gerónimo, Renotte, Nathalie, Reichert, Michal, Trono, Karina, Willems, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849745/
https://www.ncbi.nlm.nih.gov/pubmed/27123579
http://dx.doi.org/10.1371/journal.ppat.1005588