C26:0-Carnitine Is a New Biomarker for X-Linked Adrenoleukodystrophy in Mice and Man

X-linked adrenoleukodystrophy (ALD), a progressive neurodegenerative disease, is caused by mutations in ABCD1 and characterized by very-long-chain fatty acids (VLCFA) accumulation. Virtually all males develop progressive myelopathy (AMN). A subset of patients, however, develops a fatal cerebral demy...

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Detalles Bibliográficos
Autores principales: van de Beek, Malu-Clair, Dijkstra, Inge M. E., van Lenthe, Henk, Ofman, Rob, Goldhaber-Pasillas, Dalia, Schauer, Nicolas, Schackmann, Martin, Engelen-Lee, Joo-Yeon, Vaz, Frédéric M., Kulik, Wim, Wanders, Ronald J. A., Engelen, Marc, Kemp, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849772/
https://www.ncbi.nlm.nih.gov/pubmed/27124591
http://dx.doi.org/10.1371/journal.pone.0154597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849772/
https://www.ncbi.nlm.nih.gov/pubmed/27124591
http://dx.doi.org/10.1371/journal.pone.0154597

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