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HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection

BACKGROUND: Decreased hepatitis C virus (HCV) clearance, faster cirrhosis progression and higher HCV RNA levels are associated with Human Immunodeficiency virus (HIV) coinfection. The CD4(+) T helper cytokines interleukin (IL)-21 and IL-17A are associated with virus control and inflammation, respect...

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Detalles Bibliográficos
Autores principales: MacParland, Sonya A., Fadel, Saleh M., Mihajlovic, Vesna, Fawaz, Ali, Kim, Connie, Rahman, A. K. M. Nur-ur, Liu, Jun, Kaul, Rupert, Kovacs, Colin, Grebely, Jason, Dore, Gregory J., Wong, David K., Ostrowski, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849786/
https://www.ncbi.nlm.nih.gov/pubmed/27124305
http://dx.doi.org/10.1371/journal.pone.0154433