Antiviral Drug Ganciclovir Is a Potent Inhibitor of the Proliferation of Müller Glia–Derived Progenitors During Zebrafish Retinal Regeneration

PURPOSE: The purpose of this study was to investigate the effect of the antiviral drug ganciclovir (GCV) on Müller glia dedifferentiation and proliferation and the underlying cellular and molecular mechanisms in adult zebrafish. METHODS: A Tg(1016tuba1a:GFP) transgenic line was generated to identify...

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Detalles Bibliográficos
Autores principales: Zhang, Shuqiang, Mu, Zhaoxia, He, Chunjiao, Zhou, Minmin, Liu, Dong, Zhao, Xiao-Feng, Goldman, Daniel, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849886/
https://www.ncbi.nlm.nih.gov/pubmed/27096757
http://dx.doi.org/10.1167/iovs.15-18669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849886/
https://www.ncbi.nlm.nih.gov/pubmed/27096757
http://dx.doi.org/10.1167/iovs.15-18669

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