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Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration
Migratory immune cells use intracellular signaling networks to generate and orient spatially polarized responses to extracellular cues. The monomeric G protein Cdc42 is believed to play an important role in controlling the polarized responses, but it has been difficult to determine directly the cons...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850032/ https://www.ncbi.nlm.nih.gov/pubmed/26941336 http://dx.doi.org/10.1091/mbc.E15-12-0832 |