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A Cross-sectional Study of KLKB1 and PRCP Polymorphisms in Patient Samples with Cardiovascular Disease

Plasma kallikrein formed from prekallikrein (PK) produces bradykinin from kininogens and activates factor XII. Plasma PK is activated by factors αXIIa, βXIIa, or prolylcarboxypeptidase (PRCP). A cross-sectional investigation determined if there is an association of PRCP and KLKB1 polymorphisms with...

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Detalles Bibliográficos
Autores principales: Gittleman, Haley R., Merkulova, Alona, Alhalabi, Omar, Stavrou, Evi X., Veigl, Martina L., Barnholtz-Sloan, Jill S., Schmaier, Alvin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850149/
https://www.ncbi.nlm.nih.gov/pubmed/27200353
http://dx.doi.org/10.3389/fmed.2016.00017