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Biological properties of novel ruthenium- and osmium-nitrosyl complexes with azole heterocycles

Since the discovery that nitric oxide (NO) is a physiologically relevant molecule, there has been great interest in the use of metal nitrosyl compounds as antitumor pharmaceuticals. Particularly interesting are those complexes which can deliver NO to biological targets. Ruthenium- and osmium-based c...

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Detalles Bibliográficos
Autores principales: Novak, Maria S., Büchel, Gabriel E., Keppler, Bernhard K., Jakupec, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850188/
https://www.ncbi.nlm.nih.gov/pubmed/26961253
http://dx.doi.org/10.1007/s00775-016-1345-z