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Chemical Genomics Identifies the PERK-Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus Inhibition

Influenza A viruses generate annual epidemics and occasional pandemics of respiratory disease with important consequences for human health and the economy. Therefore, a large effort has been devoted to the development of new anti-influenza virus drugs directed to viral targets, as well as to the ide...

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Detalles Bibliográficos
Autores principales: Landeras-Bueno, Sara, Fernández, Yolanda, Falcón, Ana, Oliveros, Juan Carlos, Ortín, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850254/
https://www.ncbi.nlm.nih.gov/pubmed/27094326
http://dx.doi.org/10.1128/mBio.00085-16