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Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood

Bloodstream infections are a leading cause of morbidity and mortality. Early and targeted antimicrobial intervention is lifesaving, yet current diagnostic approaches fail to provide actionable information within a clinically viable time frame due to their reliance on blood culturing. Here, we presen...

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Detalles Bibliográficos
Autores principales: Nölling, Jörk, Rapireddy, Srinivas, Amburg, Joel I., Crawford, Elizabeth M., Prakash, Ranjit A., Rabson, Arthur R., Tang, Yi-Wei, Singer, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850259/
https://www.ncbi.nlm.nih.gov/pubmed/27094328
http://dx.doi.org/10.1128/mBio.00345-16