Cargando…
Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood
Bloodstream infections are a leading cause of morbidity and mortality. Early and targeted antimicrobial intervention is lifesaving, yet current diagnostic approaches fail to provide actionable information within a clinically viable time frame due to their reliance on blood culturing. Here, we presen...
Autores principales: | Nölling, Jörk, Rapireddy, Srinivas, Amburg, Joel I., Crawford, Elizabeth M., Prakash, Ranjit A., Rabson, Arthur R., Tang, Yi-Wei, Singer, Alon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850259/ https://www.ncbi.nlm.nih.gov/pubmed/27094328 http://dx.doi.org/10.1128/mBio.00345-16 |
Ejemplares similares
-
Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs
por: Crawford, Matthew J., et al.
Publicado: (2011) -
Duplex Structure of a Minimal Nucleic Acid
por: Schlegel, Mark K., et al.
Publicado: (2008) -
Selection of RNA aptamers that bind HIV-1 LTR DNA duplexes: strand invaders
por: Srisawat, Chatchawan, et al.
Publicado: (2010) -
The crystal structure of an ‘All Locked’ nucleic acid duplex
por: Eichert, André, et al.
Publicado: (2010) -
On the stability of peptide nucleic acid duplexes in the presence of organic solvents
por: Sen, Anjana, et al.
Publicado: (2007)