Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function

Invasive fungal infections remain difficult to treat and require novel targeting strategies. The 12-kDa FK506-binding protein (FKBP12) is a ubiquitously expressed peptidyl-prolyl isomerase with considerable homology between fungal pathogens and is thus a prime candidate for future targeting efforts...

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Detalles Bibliográficos
Autores principales: Tonthat, Nam K., Juvvadi, Praveen Rao, Zhang, Hengshan, Lee, Soo Chan, Venters, Ron, Spicer, Leonard, Steinbach, William J., Heitman, Joseph, Schumacher, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850266/
https://www.ncbi.nlm.nih.gov/pubmed/27118592
http://dx.doi.org/10.1128/mBio.00492-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850266/
https://www.ncbi.nlm.nih.gov/pubmed/27118592
http://dx.doi.org/10.1128/mBio.00492-16

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