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The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte. Pathogenic Histoplasma yeast cells, but not avirulent mycelial cell...

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Detalles Bibliográficos
Autores principales: Garfoot, Andrew L., Shen, Qian, Wüthrich, Marcel, Klein, Bruce S., Rappleye, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850272/
https://www.ncbi.nlm.nih.gov/pubmed/27094334
http://dx.doi.org/10.1128/mBio.01388-15