Redox-Active Sensing by Bacterial DksA Transcription Factors Is Determined by Cysteine and Zinc Content

The four-cysteine zinc finger motif of the bacterial RNA polymerase regulator DksA is essential for protein structure, canonical control of the stringent response to nutritional limitation, and thiol-based sensing of oxidative and nitrosative stress. This interdependent relationship has limited our...

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Detalles Bibliográficos
Autores principales: Crawford, Matthew A., Tapscott, Timothy, Fitzsimmons, Liam F., Liu, Lin, Reyes, Aníbal M., Libby, Stephen J., Trujillo, Madia, Fang, Ferric C., Radi, Rafael, Vázquez-Torres, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850274/
https://www.ncbi.nlm.nih.gov/pubmed/27094335
http://dx.doi.org/10.1128/mBio.02161-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850274/
https://www.ncbi.nlm.nih.gov/pubmed/27094335
http://dx.doi.org/10.1128/mBio.02161-15

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