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Redox-Active Sensing by Bacterial DksA Transcription Factors Is Determined by Cysteine and Zinc Content
The four-cysteine zinc finger motif of the bacterial RNA polymerase regulator DksA is essential for protein structure, canonical control of the stringent response to nutritional limitation, and thiol-based sensing of oxidative and nitrosative stress. This interdependent relationship has limited our...
Autores principales: | Crawford, Matthew A., Tapscott, Timothy, Fitzsimmons, Liam F., Liu, Lin, Reyes, Aníbal M., Libby, Stephen J., Trujillo, Madia, Fang, Ferric C., Radi, Rafael, Vázquez-Torres, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850274/ https://www.ncbi.nlm.nih.gov/pubmed/27094335 http://dx.doi.org/10.1128/mBio.02161-15 |
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