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MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes

The aim of this study was to determine the specific microRNA (miRNA) that regulates expression of osteopontin (OPN) in osteoarthritis (OA). The potential regulatory miRNAs for OPN messenger RNA (mRNA) were predicted by miRNA prediction programs. Among eight potential regulatory miRNAs, miR-220b, miR...

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Detalles Bibliográficos
Autores principales: Tu, Min, Li, Yusheng, Zeng, Chao, Deng, Zhenhan, Gao, Shuguang, Xiao, Wenfeng, Luo, Wei, Jiang, Wei, Li, Liangjun, Lei, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850404/
https://www.ncbi.nlm.nih.gov/pubmed/27126955
http://dx.doi.org/10.1038/srep25032