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Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells
Natural variations in gene expression provide a mechanism for multiple phenotypes to arise in an isogenic bacterial population. In particular, a sub-group termed persisters show high tolerance to antibiotics. Previously, their formation has been attributed to cell dormancy. Here we demonstrate that...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850422/ https://www.ncbi.nlm.nih.gov/pubmed/27105118 http://dx.doi.org/10.1016/j.molcel.2016.03.035 |