Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells

Natural variations in gene expression provide a mechanism for multiple phenotypes to arise in an isogenic bacterial population. In particular, a sub-group termed persisters show high tolerance to antibiotics. Previously, their formation has been attributed to cell dormancy. Here we demonstrate that...

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Detalles Bibliográficos
Autores principales: Pu, Yingying, Zhao, Zhilun, Li, Yingxing, Zou, Jin, Ma, Qi, Zhao, Yanna, Ke, Yuehua, Zhu, Yun, Chen, Huiyi, Baker, Matthew A.B., Ge, Hao, Sun, Yujie, Xie, Xiaoliang Sunney, Bai, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850422/
https://www.ncbi.nlm.nih.gov/pubmed/27105118
http://dx.doi.org/10.1016/j.molcel.2016.03.035

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