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Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

Hematopoietic stem cells (HSCs) reside in a perivascular niche but the location remains controversial(1). HSCs are rare and few can be found in thin tissue sections(2,3) or upon live imaging(4), making it difficult to comprehensively localize dividing and non-dividing HSCs. We discovered that α-catu...

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Detalles Bibliográficos
Autores principales: Acar, Melih, Kocherlakota, Kiranmai S., Murphy, Malea M., Peyer, James G., Oguro, Hideyuki, Inra, Christopher N., Jaiyeola, Christabel, Zhao, Zhiyu, Luby-Phelps, Katherine, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850557/
https://www.ncbi.nlm.nih.gov/pubmed/26416744
http://dx.doi.org/10.1038/nature15250