The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia

BACKGROUND: Opioids are a mainstay for the treatment of chronic pain. Unfortunately, therapy-limiting maladaptations such as loss of treatment effect (tolerance), and paradoxical opioid-induced hyperalgesia (OIH) can occur. The objective of this study was to identify genes responsible for opioid tol...

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Detalles Bibliográficos
Autores principales: Donaldson, Robin, Sun, Yuan, Liang, De-Yong, Zheng, Ming, Sahbaie, Peyman, Dill, David L., Peltz, Gary, Buck, Kari J., Clark, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850636/
https://www.ncbi.nlm.nih.gov/pubmed/27129385
http://dx.doi.org/10.1186/s12864-016-2634-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850636/
https://www.ncbi.nlm.nih.gov/pubmed/27129385
http://dx.doi.org/10.1186/s12864-016-2634-1

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