Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways

BACKGROUND: Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate immune network in the retina after nerve damage has been linked to RGC pathology. Since the eye is immune privileged, innate immune f...

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Detalles Bibliográficos
Autores principales: Mac Nair, Caitlin E., Schlamp, Cassandra L., Montgomery, Angela D., Shestopalov, Valery I., Nickells, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850653/
https://www.ncbi.nlm.nih.gov/pubmed/27126275
http://dx.doi.org/10.1186/s12974-016-0558-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850653/
https://www.ncbi.nlm.nih.gov/pubmed/27126275
http://dx.doi.org/10.1186/s12974-016-0558-y

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