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Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor

A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trélat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to p...

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Detalles Bibliográficos
Autores principales: Mathez, Andreia Latanza Gomes, Moroto, Debora, Dib, Sergio Atala, de Sa, Joao Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850662/
https://www.ncbi.nlm.nih.gov/pubmed/27134683
http://dx.doi.org/10.1186/s13098-016-0148-2